Recently in my research project, I extracted DNA from an environmental sample and conducted both metagenomic sequencing and amplicon sequencing. The MAGs were classified using GTDB-tk, while the taxonomy of the ASVs was assigned with SILVA.
Now I have an issue matching the MAGs and ASVs from the same species. I selected some ASVs of interest and hope to find the corresponding MAGs of the same species for downstream analysis. However, due to significant differences in the species nomenclature between the two databases, direct comparison of the annotation results is challenging.
I’m wondering if you could provide guidance or suggest methods to match GTDB taxonomy names with SILVA. Or are there any recommended approaches or tools that could assist in matching 16S rRNA gene sequences with MAGs?
Thanks for your help!